Chelsea host Shamrock Rovers with hopes of securing top spot, while Vitória SC and Fiorentina carry top-eight ambitions into their Matchday 6 meeting as the inaugural UEFA Conference League league phase comes to an end on Thursday, according to the official website of UEFA.
After a Marc Guiu-inspired win in Almaty, Chelsea are the only side to confirm their place in the round of 16, carrying the last remaining 100% record into their final league phase contest – a home meeting with Shamrock Rovers.
Unbeaten Shamrock Rovers travel to west London after their third win of the campaign – a 3-0 triumph against Borac at Tallaght Stadium – propelled them to sixth in the league phase table.
Shamrock Rovers are the first Irish club to reach the knockout stages of a UEFA competition.
Second meets third as Vitória SC take on Fiorentina in Guimaraes with both sides eyeing a top-eight finish after emphatic Matchday 5 wins.
Fresh from a 7-0 win over LASK, the club's biggest European victory, Fiorentina are in similarly fearsome form.
Fiorentina have lost just three of their 14 encounters with Portuguese sides in UEFA competitions (W7 D4), their last defeat against Benfica in 1997.
Thursday's Conference League fixtures are as follows:
Heidenheim vs St. Gallen
APOEL vs Astana
Cercle Brugge vs İstanbul Başakşehir
Chelsea vs Shamrock Rovers
Djurgården vs Legia Warszawa
Lugano vs Pafos
Borac vs Omonoia
TSC vs Noah
Hearts vs Petrocub
Jagiellonia Białystok vs Olimpija Ljubljana
Larne vs Gent
LASK vs Víkingur Reykjavík
Molde vs Mladá Boleslav
Celje vs The New Saints
Panathinaikos vs Dinamo-Minsk
Real Betis vs HJK Helsinki
Rapid Wien vs Copenhagen
Vitória SC vs Fiorentina